2-Pyridinemethanamine → HCID 20374345, compound

HRID 1834318Notes

Reaction equation

HRID 1834318 reaction equation
ClC1C=C(C=CC=1)C(Cl)=O.[F:11][S:12]([C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18](Cl)=[O:19])(=[O:14])=[O:13].[NH2:24][CH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][N:27]=1>>[F:11][S:12]([C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18]([NH:24][CH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][N:27]=1)=[O:19])(=[O:14])=[O:13]

Participants

4

Reactant 3

HCID 195092-PyridinemethanamineHCID 67991Benzoyl chloride, 3-(fluorosulfonyl)-HCID 69252Benzoyl chloride, 3-chloro-

Product 1

HCID 20374345HCID 20374345, compound

Procedure

Following the procedure of Example 6, Part A, supra., but replacing the 3-chlorobenzoyl chloride as used therein with 6.68 gms. (0.03 mole) of 3-fluorosulfonylbenzoyl chloride and reducing the proportion of 2-aminomethylpyridine as used therein to 3.24 gms. (0.03 mole) there is obtained 3-fluorosulfonyl-N-(2-pyridylmethyl)benzamide in the form of a tan colored solid.

Sources & evidence

ORD record
ord-d4dd100f92b7424696a7dd3c32ebe688
Source dataset
uspto-grants-1978_01
Patent number
US04069224

Reaction notes

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