Triethylamine → HCID 20307399, compound

Participants

Reaction Steps

To 40 parts of tetrahydrofuran are added 1.4 parts of 3-amino-1-propanol and 1.8 parts of triethylamine. Into this solution, 10 parts of tetrahydrofuran containing 5 parts of 2,4,6-trichlorobenzenesulfonyl chloride is dropped with stirring. After the dropping, the resultant mixture is stirred for 1 hour. After completion of the reaction, the salt is removed by filtration, and the filtrate is freed from the solvent. The resulting oily substance is charged with water and then allowed to stand to form a solid. This solid is recrystallized from toluene to obtain 3.8 parts of N-3-hydroxypropyl-2,4,6-trichlorobenzenesulfonamide, m.p. 104.5°-106.5° C.

Provenance & Evidence