L-Proline → HCID 53816684, compound

HRID 1834366Notes

Reaction equation

HRID 1834366 reaction equation
C([S:4][CH2:5][CH:6]([S:8]([N:11]1[CH2:18][CH2:17][CH2:16][C@H:12]1[C:13]([OH:15])=[O:14])(=[O:10])=[O:9])[CH3:7])(=O)C.C(SCCS(N1CCC[C@H]1C(O)=O)(=O)=O)(=O)C.N1CCC[C@H]1C(O)=O>>[SH:4][CH2:5][CH:6]([S:8]([N:11]1[CH2:18][CH2:17][CH2:16][C@H:12]1[C:13]([OH:15])=[O:14])(=[O:10])=[O:9])[CH3:7]

Participants

4

Reactant 3

HCID 145742L-ProlineHCID 14181428HCID 14181428, compoundHCID 54303139HCID 54303139, compound

Product 1

HCID 53816684HCID 53816684, compound

Procedure

By substituting 1-[[2-(Acetylthio)-1-methylethyl]-sulfonyl]-L-proline for the 1-[[2-(acetylthio)ethyl]sulfonyl]-L-proline in the procedure of Example 2, 1-[2-mercapto-1-methylethyl)sulfonyl]-L-proline is obtained.

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-907def5ba6704733b641d05b5c26d7e5
Source dataset
uspto-grants-1978_01
Patent number
US04070361

Reaction notes

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