Ammonium Hydroxide → HCID 5055125, compound

Participants

Reaction Steps

2,4-Dimethyl-3-carbethoxy-pyrrole (0.668 g) was dissolved in a mixture of hydriodic acid (10 ml), acetic anhydride (10 ml) and hypophosphorous acid (2 ml). Paraldehyde (0.75 ml) was added. The solution was stirred 5 min., decolorized with phosphonium iodide, and poured into ice water. The cooled mixture was brought to pH 8 with ammonium hydroxide. The product was filtered off and distilled (90°-100°, 5 × 10-4 mm), giving colourless crystals (53%), m.p. 108°-109° after changing to prisms at 105°. For analysis, it was recrystallized from hexane as prismatic rods, m.p. 107°-109° (lit17) 106°-107°).

Provenance & Evidence