1H-Pyrrole-2-carboxylic acid, 3,5-dimethyl-, ethyl ester → HCID 20373148, compound

HRID 1834448Notes

Reaction equation

HRID 1834448 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:5]([CH3:7])[CH:6]=1>CC(=O)CC>[CH3:1][C:2]1[NH:3][C:4]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:5]([CH3:7])[C:6]=1[CH:2]([CH2:6][CH3:5])[CH3:1]

Participants

3

Reactant 1

HCID 1374771H-Pyrrole-2-carboxylic acid, 3,5-dimethyl-, ethyl ester

Product 1

HCID 20373148HCID 20373148, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

The crude product, obtained as in Example 74 but using 2,4-dimethyl-5-carbethoxypyrrole with 2-butanone and stirring at 30°-35° C, was sublimed then thrice recrystallized from ethanol as colorless plates (130 mg), m.p. 102°-104° C.

Workup

  1. customthrice recrystallized from ethanol as colorless plates (130 mg), m.p. 102°-104° C.

Sources & evidence

ORD record
ord-cb05d921108e415988506d2f207a76cb
Source dataset
uspto-grants-1978_01
Patent number
US04070366

Reaction notes

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