Formaldehyde → 2,4,5-Trimethyl-3-isobutyl pyrrole

HRID 1834466Notes

Reaction equation

[C:1]([C:6]1[NH:7][C:8]([CH3:16])=[C:9]([CH3:15])[C:10]=1[CH2:11][CH:12]([CH3:14])[CH3:13])(OCC)=O.C=O>>[CH3:1][C:6]1[NH:7][C:8]([CH3:16])=[C:9]([CH3:15])[C:10]=1[CH2:11][CH:12]([CH3:14])[CH3:13]

Participants

Reactant 2

HCID 712Formaldehyde

HCID 20373134HCID 20373134, compound

Product 1

HCID 203731332,4,5-Trimethyl-3-isobutyl pyrrole

Procedure

2-Carbethoxy-3-isobutyl-4,5-dimethyl-pyrrole was reductively alkylated with paraformaldehye to yield 2,4,5-trimethyl-3-isobutyl pyrrole. ##STR107##

Sources & evidence

ORD record: ord-f93acadb5e104d288b9edec58544c7b7
Source dataset: uspto-grants-1978_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04070366

Reaction notes

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