Formaldehyde → HCID 21728753, compound

HRID 1834469Notes

Reaction equation

HRID 1834469 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:15](OCC)=O)=[C:5]([CH3:14])[C:6]=1[CH2:7][CH2:8][C:9]([O:11]CC)=[O:10].C=O>>[CH3:1][C:2]1[NH:3][C:4]([CH3:15])=[C:5]([CH3:14])[C:6]=1[CH2:7][CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 712FormaldehydeHCID 291761Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate

Product 1

HCID 21728753HCID 21728753, compound

Procedure

2,4-Dimethyl-3-carbethoxy ethyl-5-carbethoxy-pyrrole was reductively alkylated with paraformaldehyde to yield 2,4,5-trimethyl-3-carboxyethyl-pyrrole. ##STR110##

Sources & evidence

ORD record
ord-3a095a1633794ef68e8e0d2905eaa4c7
Source dataset
uspto-grants-1978_01
Patent number
US04070366

Reaction notes

Loading…