{1-[4-(6-Fluoro-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester → {1-[4-(8-Bromo-7-methoxy-4-oxo-2-phenyl-4H-chromen-3-yl)-phenyl]-cyclobutyl}-carbamic acid tert-butyl ester
Reaction equation
[Br:37][c:38]1[c:39]([O:56][CH3:57])[cH:40][cH:41][c:42]2[c:43](=[O:55])[c:44]([I:54])[c:45](-[c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)[o:46][c:47]12.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19](=[O:20])[c:21]4[c:22]([cH:23][cH:24][c:25]([F:26])[cH:27]4)[o:28][c:29]3-[c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([c:12]2[cH:13][cH:14][c:15](-[c:44]3[c:43](=[O:55])[c:42]4[cH:41][cH:40][c:39]([O:56][CH3:57])[c:38]([Br:37])[c:47]4[o:46][c:45]3-[c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)[cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)=[O:36]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-bd5ce333835c499c9cd20ca1121878b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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