Acetic Anhydride → 3-Acetoxy-2-dodecyl-5-methyl-1,4-naphthoquinone

Participants

Reaction Steps

3.8 Parts of 2-dodecyl-3-hydroxy-5-methyl-1,4-naphthoquinone, 8parts of acetic anhydride and 32 parts of pyridine were stirred at room temperature for 16 hours. The resulting mixture was evaporated under reduced pressure to remove the pyridine. The residue was recrystallized from methanol to give 2.5 parts of 3-acetoxy-2-dodecyl-5-methyl-1,4-naphthoquinone, m.p. 69°-74° C.

Provenance & Evidence