HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → 1,2-bis-[N'-(2-(5-Methyl-4-imidazolylmethylthio)ethyl)guanidino]ethane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | S-methyl-N-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]thiouronium sulphate | HCID 20242495 | — |
| Product | 1,2-bis-[N'-(2-(5-Methyl-4-imidazolylmethylthio)ethyl)guanidino]ethane | HCID 54477039 | — |
Reaction Steps
The reaction of 1,2-diaminoethane (0.60 g) with S-methyl-N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiouronium sulphate (5.86 g) by the method described in Example 5 afforded the title compound which was isolated as the dipicrate (3.5 g), m.p. 201°-203°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04070472 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-e0d4d58764f04ea9bcc61047d1f3fa0b |
| Source note | uspto-grants-1978_01 |