HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-(pyrazinylmethyl)ethylenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Pyrazine, 2-(chloromethyl)- | HCID 170169 | — |
| Product | N-(pyrazinylmethyl)ethylenediamine | HCID 13910894 | — |
Reaction Steps
Ethylenediamine is reacted with 2-chloromethylpyrazine by the procedure of Example 34 to give N-(2-pyrazinylmethyl)ethylenediamine. Heating this compound with S-methylisothiourea in water under reflux for 3 hours by the procedure of Example 1 gives 2-(2-pyrazinyl)methylamino)ethylguanidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04070475 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-d06ef580f9c34b54b75b48a6fc6c9356 |
| Source note | uspto-grants-1978_01 |