HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyano-2,3-dimethylisothiourea → HCID 178484996, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyano-2,3-dimethylisothiourea | HCID 111103 | — |
| Reactant | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| Product | HCID 178484996 | HCID 178484996 | — |
Reaction Steps
Reaction of [(2-aminoethyl)thiomethyl]thiazole (from the dihydrobromide 20.2 g.) with N-cyano-N',S-dimethyl isothiourea (7.75 g.) by a procedure similar to that described in Example 3(a) afforded N-cyano-N'-methyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine, m.p. 120°-122.5°, following chromatography on silica gel with acetonitrile as eluant, and recrystallisation from isopropyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04070475 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-58e0400acc7a4b2b85b5b498dddf013e |
| Source note | uspto-grants-1978_01 |