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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1834656Generated: October 26, 2026

Ethylenediamine → N-[2-(2-(2-Benzimidazolyl)ethylamino)ethyl]-N'-cyano-N"-methylguanidine

https://huagongshe.com/reaction/1834656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant1-Cyano-2,3-dimethylisothioureaHCID 111103—
Reactant2-(2-Chloroethyl)benzimidazoleHCID 12216288—
ReactantN-[2-(2-benzimidazolyl)ethyl]ethylenediamineHCID 20567701—
ProductN-[2-(2-(2-Benzimidazolyl)ethylamino)ethyl]-N'-cyano-N"-methylguanidineHCID 53646889—

Reaction Steps

Reacting 2-(2-chloroethyl)benzimidazole with ethylenediamine by the procedure of Example 34, then reacting the resulting N-[2-(2-benzimidazolyl)ethyl]-ethylenediamine with N-cyano-N',S-dimethylisothiourea by the procedure of Example 3(a) gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04070475
Source datasetuspto-grants-1978_01
ORD IDord-bd47a26fb1064dc08b3256c09be3a136
Source noteuspto-grants-1978_01