反应详情

(1-Oxo-2-ethyl-6-chloro-5-indanyloxy)acetic acid is prepared by following substantially the same procedure as described in Example 1, Step A, using the following reagents: [2-chloro-4-(2-methylenebutyryl)phenoxy]acetic acid (41.32 g., 0.154 mole) and conc. sulfuric acid (165 ml.). The crude yield of the product is 38.8 g. (94%), m.p. 132°-138° C. Recrystallization from benzene gives (1-oxo-2-ethyl-6-chloro-5-indanyloxy)acetic as white prisms, m.p. 142°-144° C.

1. customRecrystallization from benzene