Sulfuryl chloride → 4-(1-Oxo-2-ethyl-2,6,7-trichloro-5-indanyloxy)-butyric Acid

HRID 1834700Notes

Reaction equation

HRID 1834700 reaction equation
[O:1]=[C:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH2:4][CH:3]1[CH2:20][CH3:21].S(Cl)([Cl:25])(=O)=O>C(O)(=O)C>[O:1]=[C:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH2:4][C:3]1([CH2:20][CH3:21])[Cl:25]

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 203739044-(1-Oxo-2-ethyl-6,7-dichloro-5-indanyloxy)-butyric Acid

Product 1

HCID 203738644-(1-Oxo-2-ethyl-2,6,7-trichloro-5-indanyloxy)-butyric Acid

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

By following the method of Example 12, Step B, 4-(1-oxo-2ethyl-6,7-dichloro-5-indanyloxy)butyric acid (13.24 g., 0.04 mole) is treated with sulfuryl chloride (3.6 ml., 0.044 mole) in acetic acid (100 ml.) to obtain 9.33 g. of 4-(1-oxo-2-ethyl-2,6,7-trichloro-5-indanyloxy)butyric acid, m.p. 123°-124° C. after recrystallization from ethanol.

Workup

  1. customto obtain 9.33 g
  2. customof 4-(1-oxo-2-ethyl-2,6,7-trichloro-5-indanyloxy)butyric acid, m.p. 123°-124° C. after recrystallization from ethanol

Sources & evidence

ORD record
ord-e3ea7f7f2f294fda8ce8d363f09e5e0c
Source dataset
uspto-grants-1978_01
Patent number
US04070539

Reaction notes

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