反应详情

5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-fluorouridine (4 g) was treated with trifluoroacetic acid/water (9:1, 30 ml) for 15 minutes at room temperature. The solution was evaporated to dryness, co-evaporated with ethanol (2 × 100 ml) and the residue was recrystallized from ethyl acetate. Yield = 1.865 g (88%).

1. customThe solution was evaporated to dryness, co-evaporated with ethanol (2 × 100 ml)
2. customthe residue was recrystallized from ethyl acetate