HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 17beta,19-Dihydroxy-1alpha-methyl-5alpha-androstan-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 17beta,19-Dihydroxy-1alpha-methyl-5alpha-androstan-3-one dipropionate | HCID 86735425 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 17beta,19-Dihydroxy-1alpha-methyl-5alpha-androstan-3-one | HCID 70615096 | — |
Reaction Steps
A solution of 17β,19-dihydroxy-1α-methyl-5α-androstan-3-one dipropionate in methanol is refluxed for two hours with aqueous sodium carbonate. The methanol is removed under vacuum and water added to the residue. Crystallization of the solid residue from an acetone-hexane solution yields pure 17β,19-dihydroxy-1α-methyl-5α-androstan-3-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04071625 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-d04e4e0a71514b40b1be37c5d4208fb2 |
| Source note | uspto-grants-1978_01 |