HuagongsheHuagongshe Chemistry Print Report · For research reference only
5alpha-Androstane-3beta,17beta,19-triol → 3beta,17beta,19-Tri(triphenylsiloxy)-5alpha-androstane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5alpha-Androstane-3beta,17beta,19-triol | HCID 15818506 | — |
| Reactant | 1alpha,7alpha-Dimethyl-17beta,19-di(triphenylsiloxy)-5alpha-androstan-3-one | HCID 22801530 | — |
| Product | 3beta,17beta,19-Tri(triphenylsiloxy)-5alpha-androstane | HCID 22801534 | — |
| Product | 19-Hydroxy-3beta-triphenylsiloxy-5alpha-androstan-17-one acetate | HCID 86735436 | — |
| Product | 3-Hydroxy-19-triphenylsiloxy-5alpha-androstan-17-one acetate | HCID 131711026 | — |
Reaction Steps
Substituting 5α-androstane-3β,17β,19-triol, 3β,19-dihydroxy-5α-androstan-17-one 19-acetate and 3β,19-dihydroxy-5α-androstan-17-one 3-acetate for the 17β,19-dihydroxy-1α,7α-dimethyl-5α-androstan-3-one above results in the preparation of 3β,17β,19-tri(triphenylsiloxy)-5α-androstane, 19-hydroxy-3β-triphenylsiloxy-5α-androstan-17-one acetate and 3-hydroxy-19-triphenylsiloxy-5α-androstan-17-one acetate, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04071625 |
| Source dataset | uspto-grants-1978_01 |
| ORD ID | ord-3886fbb338da43f5852c6d1f70cbb143 |
| Source note | uspto-grants-1978_01 |