HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyacetonitrile → N-carboxymethyl-N-cyanomethylamino-2-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyacetonitrile | HCID 7857 | — |
| Reactant | N-(2-Hydroxyethyl)glycine | HCID 225935 | — |
| Product | N-carboxymethyl-N-cyanomethylamino-2-ethanol | HCID 11073690 | — |
Reaction Steps
The hydrolysis of (I) with base gives N-carboxymethylamino-2-ethanol (II). Compound (II) is then reacted with additional glycolonitrile to form N-carboxymethyl-N-cyanomethylamino-2-ethanol (III). The molar ratio of (II) to glycolonitrile is generally about 1:1. In the above reactions, hydrogen cyanide and formaldehyde can be substituted for glycolonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05726341 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-2bfdd368208a447a97e7268f9780631d |
| Source note | uspto-grants-1998_03 |