N,N-Dimethyl-1,3-propanediamine → Stearamidopropyl Dimethylamine

Participants

Reaction Conditions

Reaction Steps

(a-2) was synthesized by a de-methanol amidation reaction between methyl stearate and N,N-dimethyl-1,3-propanediamine. Specifically, a four-neck flask equipped with a stirrer, a temperature gage and a dewatering pipe was charged with 161 g of N,N-dimethyl-1,3-propanediamine and 448 g of methyl stearate and the mixture was raised to 180° C. The mixture was heated under stirring at this temperature for about 5 hours while distilling generated methanol. The reaction mixture was cooled to 120° C. and unreacted amine was distilled under reduced pressure to obtain 545 g of the target N-stearoylaminopropyl-N,N-dimethylamine (a-2).

Provenance & Evidence