HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 23502896, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 8-amino-7-nitro-5H-phenanthridin-6-one | HCID 11379823 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 23502896 | HCID 23502896 | 71% |
Reaction Steps
A mixture of 8-amino-7-nitro-5H-phenanthridin-6-one (412 mg, 1.62 mmol), Pd/C (10 wt %, 234 mg) in TFA was hydrogenated at 50 psi for 50 min. The catalyst was filtered through a plug of diatomaceous earth and rinsed with ethanol. The solvent was evaporated to obtain 7,8-diamino-5H-phenanthridin-6-one trifluoroacetate salt (520 mg, 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06770639B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-39224ead76884bc287b5b7bfeea1b8fe |
| Source note | uspto-grants-2004_08 |