Hydrochloric Acid → HCID 23503234, compound

Participants

Reaction Steps

Ethyl 4-(3-methyl-1-oxobutyl)-1H-pyrazole-5-carboxylate (Example 32, step c; 0.62 g), 1-naphthalenylmethyl chloride (0.53 g), and cesium carbonate (1.1 g) were stirred in dry dimethylformamide (8 ml) for 48 hours, and then dilute hydrochloric acid was added. The mixture was extracted with ethyl acetate, which was washed with brine, dried, and evaporated to give ethyl 4-(3-methyl-1-oxobutyl)-1-(1-naphthalenylmethyl)-1H-pyrazole-3-carboxylate as a gum. (0.15 g)

Provenance & Evidence