HCID 23503598, compound → 4-(2,3,4-Trimethoxy-6-methylbenzoyl)-2,3,5-trichloropyridine

Participants

Reaction Steps

16.2 g of manganese dioxide was added to a toluene (180 ml) solution of 5.6 g of (2,3,4-trimethoxy-6-methylphenyl)(2,3,5-trichloro-4-pyridyl)methanol obtained in step (a), followed by stirring under reflux by heating for 3 hours. After the mixture was cooled, it was subjected to filtration, and the solvent was distilled off under reduced pressure to obtain 4.7 g (yield 87%) of 4-(2,3,4-trimethoxy-6-methylbenzoyl)-2,3,5-trichloropyridine (compound No. 186; m.p. 60-61° C.).

Provenance & Evidence