4,5-Dimethyl-1-(3-nitrophenyl)imidazole → 3-(4,5-Dimethylimidazol-1-yl)phenylamine

Participants

Reaction Steps

A suspension of 4,5-dimethyl-1-(3-nitrophenyl)imidazole (130 mg) in methanol (2 ml) and tetrahydrofuran (2 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 50 mg) under hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 3-(4,5-dimethyl-imidazol-1-yl)aniline (110 mg, 98.2%).

Provenance & Evidence