HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile → 2-(4-Amino2-chlorophenylsulfanyl)-benzothiazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile | HCID 22148751 | — |
| Reactant | Tin tetrachloride dihydrate | HCID 85782573 | — |
| Product | 2-(4-Amino2-chlorophenylsulfanyl)-benzothiazole-5-carbonitrile | HCID 22148905 | 93% |
Reaction Steps
The title compound was prepared using the method of example 270, starting with 2-(2-chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile (263) (1.59 g, 4.58 mmol), tin chloride dihydrate (Aldrich, 5.18 g, 22.9 mmol). Compound 275 (1.35 g, 93%) was obtained as a yellowish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06770648B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-0a1b5f12fb6444faa0e01f08df0cd66a |
| Source note | uspto-grants-2004_08 |