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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1835575Generated: October 26, 2026

2-Bromo-5-methoxybenzyl bromide → Ethyl 2-[4-(2-bromo-5-methoxybenzyloxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate

https://huagongshe.com/reaction/1835575

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-methoxybenzyl bromideHCID 3525951—
ReactantEthyl 1-cyclohexyl-2-(4-hydroxyphenyl)benzimidazole-5-carboxylateHCID 135486203—
ProductEthyl 2-[4-(2-bromo-5-methoxybenzyloxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylateHCID 10120450—

Reaction Steps

Ethyl 1-cyclohexyl-2-(4-hydroxyphenyl)benzimidazole-5-carboxylate obtained in Example 3 and 2-bromo-5-methoxybenzyl bromide were treated in the same manner as in Example 4 to give the title compound (59 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06770666B2
Source datasetuspto-grants-2004_08
ORD IDord-47fb135e3d7946a0a06c857e2337772a
Source noteuspto-grants-2004_08