Lauric Acid → Dodecanoyl chloride

Participants

Reaction Steps

82.2 g (1.13 mol) of N,N-dimethylformamide were added to 4.5 mol of lauric acid in a stirred apparatus. The reaction solution was brought to a temperature of from 40 to 50° C. with stirring, and a total of 5.06 mol of gaseous phosgene were introduced under atmospheric pressure. After the addition of phosgene was complete, the two phases were separated from one another. The catalyst phase comprised a molar proportion of the catalyst adduct, based on the molar amount of N,N-dimethylformamide plus catalyst adduct, of 0.50. The carbonyl chloride phase comprised 99.1 area % of lauroyl chloride and 0.15 area % of lauric acid. The color number was 268 APHA.

Provenance & Evidence