Pyridine → HCID 53916417, compound

Participants

Reaction Conditions

Reaction Steps

Pyridine (0.6 g, 7.5 mmol) and Cobalt (ii) acetate (1.3 g, 7.5 mmol) were dissolved in DMF to produce a blue solution of the complex to which was added 4-pyridine carboxaldehyde (5 g, 46.7 mmol) and acetophenone (6.2 g, 51.4 mmol). The resulting mixture was stirred for 18 hours at 90° C. Most of the DMF was evaporated in vacuo and the residue was purified by flash chromatography (silica gel) with 30% EtoAc/Hexane to afford the titled compound, white solid (5 g). ESP+ (Mass Spec) m/z 210 (MH+).

Provenance & Evidence