5-Amino-1-naphthol → 5-Amino-2-[(2,3-dimethoxyphenyl)-morpholin-4-yl-methyl)-naphthalen-1-ol

HRID 1835776Notes

Reaction equation

HRID 1835776 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[C:7]2[OH:12].[Cl-].[CH3:14][O:15][C:16]1[C:28]([O:29][CH3:30])=[CH:27][CH:26]=[CH:25][C:17]=1[CH:18]=[N+:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([CH:18]([C:17]1[CH:25]=[CH:26][CH:27]=[C:28]([O:29][CH3:30])[C:16]=1[O:15][CH3:14])[N:19]1[CH2:20][CH2:21][O:22][CH2:23][CH2:24]1)=[C:7]2[OH:12]

Participants

3

Reactant 2

HCID 657465-Amino-1-naphtholHCID 221747594-(2,3-Dimethoxy-benzylidene)-morpholin-4-ium chloride

Product 1

HCID 102006645-Amino-2-[(2,3-dimethoxyphenyl)-morpholin-4-yl-methyl)-naphthalen-1-ol

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 5-amino-1-naphthol and 4-(2,3-dimethoxy-benzylidene)-morpholin-4-ium chloride, which had been prepared in accordance with example 21.

Workup

  1. customhad been prepared in accordance with example 21

Sources & evidence

ORD record
ord-11af374129d54c93a71507a70f251540
Source dataset
uspto-grants-2004_08
Patent number
US06774136B2

Reaction notes

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