6-Bromo-2-naphthalenol → 6-Bromo-1-[(2-methoxyphenyl)-morpholin-4-yl-methyl]-naphthalen-2-ol

HRID 1835781Notes

Reaction equation

HRID 1835781 reaction equation
[Cl-].[CH3:2][O:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH:6]=[N+:7]1[CH2:12][CH2:11][O:10][CH2:9][CH2:8]1.[Br:17][C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][CH:27]=1)[CH:24]=[C:23]([OH:28])[CH:22]=[CH:21]2>>[Br:17][C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][CH:27]=1)[C:24]([CH:6]([C:5]1[CH:13]=[CH:14][CH:15]=[CH:16][C:4]=1[O:3][CH3:2])[N:7]1[CH2:8][CH2:9][O:10][CH2:11][CH2:12]1)=[C:23]([OH:28])[CH:22]=[CH:21]2

Participants

3

Reactant 2

HCID 271446-Bromo-2-naphthalenolHCID 155519114-(2-Methoxy-benzylidene)-morpholin-4-ium chloride

Product 1

HCID 235008816-Bromo-1-[(2-methoxyphenyl)-morpholin-4-yl-methyl]-naphthalen-2-ol

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 4-(2-methoxy-benzylidene)-morpholin-4-ium chloride and 6-bromo-2-naphthol.

Sources & evidence

ORD record
ord-0dbb800cc4e34d7b8e169393a17f3eb1
Source dataset
uspto-grants-2004_08
Patent number
US06774136B2

Reaction notes

Loading…