HuagongsheHuagongshe Chemistry Print Report · For research reference only
Spiro[indoline-3,3'-perhydroazepin]-2-one hydrochloride → Spiro[indoline-3,3'-perhydroazepin]-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Spiro[indoline-3,3'-perhydroazepin]-2-one hydrochloride | HCID 23500654 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Spiro[indoline-3,3'-perhydroazepin]-2-one | HCID 23500655 | — |
Reaction Steps
Spiro[indoline-3,3′-perhydroazepin]-2-one hydrochloride. The compound from the previous step was hydrogenated in acetic acid over 10% Pd/C at 40 psi H, for 48 h. Evaporation and extractive work-up gave the title compound as a yellow solid (1.51 g). MS (TSP+) m/z: 217 (M+H+, 100) which was converted to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06774132B1 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-6486a40a7c8c450a86650e2eaed5f1d9 |
| Source note | uspto-grants-2004_08 |