HCID 22179010, compound → HCID 23517409, compound

HRID 1835970Notes

Reaction equation

HRID 1835970 reaction equation
[CH3:1][C:2]([OH:10])([CH2:8][CH3:9])[CH2:3][CH2:4][CH2:5][CH2:6][OH:7].[CH:11]12[CH:20]3[CH2:21][CH:17]([CH:18]=[CH:19]3)[CH:16]1[CH:15]1[CH2:22][CH:12]2[CH:13]([CH2:23][CH2:24][C:25](OC)=[O:26])[CH2:14]1>>[CH:11]12[CH:20]3[CH2:21][CH:17]([CH:18]=[CH:19]3)[CH:16]1[CH:15]1[CH2:22][CH:12]2[CH:13]([CH2:23][CH2:24][C:25]([O:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]([OH:10])([CH3:1])[CH2:8][CH3:9])=[O:26])[CH2:14]1

Participants

3

Reactant 2

HCID 22179010HCID 22179010, compoundHCID 86585297HCID 86585297, compound

Product 1

HCID 23517409HCID 23517409, compoundYield 87%

Procedure

By following the procedure of Synthesis Example 2 except that 5-methyl-1,5-heptanediol was used instead of 4-methyl-1,4-pentanediol and methyl 3-(8-tetracyclo-[4.4.0.12,5.17,10]dodecen-3-yl)propionate used instead of methyl 5-norbornene-2-carboxylate, there was obtained 5-hydroxy-5-methylheptyl 3-(8-tetracyclo[4.4.0.12,5.17,10]-dodecen-3-yl)propionate. Yield 87%.

Sources & evidence

ORD record
ord-4ed5f0dc424749548c980b290ba616d2
Source dataset
uspto-grants-2004_08
Patent number
US06774258B2

Reaction notes

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