1-(3-Hydroxypropyl)cyclopentan-1-ol → HCID 23517407, compound

HRID 1835971Notes

Reaction equation

HRID 1835971 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][C:5]1([OH:10])[CH2:9][CH2:8][CH2:7][CH2:6]1.[CH:11]12[CH:20]3[CH2:21][CH:17]([CH:18]=[CH:19]3)[CH:16]1[CH:15]1[CH2:22][CH:12]2[CH:13]([C:23](OC)=[O:24])[CH2:14]1>>[CH:11]12[CH:20]3[CH2:21][CH:17]([CH:18]=[CH:19]3)[CH:16]1[CH:15]1[CH2:22][CH:12]2[CH:13]([C:23]([O:1][CH2:2][CH2:3][CH2:4][C:5]2([OH:10])[CH2:9][CH2:8][CH2:7][CH2:6]2)=[O:24])[CH2:14]1

Participants

3

Reactant 2

HCID 125251681-(3-Hydroxypropyl)cyclopentan-1-olHCID 20753552HCID 20753552, compound

Product 1

HCID 23517407HCID 23517407, compoundYield 88%

Procedure

By following the procedure of Synthesis Example 2 except that 1-(3-hydroxypropyl)cyclopentanol was used instead of 4-methyl-1,4-pentanediol and methyl 8-tetracyclo-[4.4.0.12,5.17,10]dodecene-3-carboxylate used instead of methyl 5-norbornene-2-carboxylate, there was obtained 3-(1-hydroxycyclopentyl)propyl 8-tetracyclo[4.4.0.12,5.17,10]-dodecene-3-carboxylate. Yield 88%.

Sources & evidence

ORD record
ord-521f45853dd745c5867bc86954ca8ccf
Source dataset
uspto-grants-2004_08
Patent number
US06774258B2

Reaction notes

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