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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836Generated: October 26, 2026

Water → (2-Hydroxyethyl)iminodiacetic acid

https://huagongshe.com/reaction/1836

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantMurexideHCID 18275—
ReactantSodium AcetateHCID 517045—
ReactantAmmonium 5-(2,4,6-trioxoperhydropyrimidin-5-ylideneamino)barbiturateHCID 14453351—
CatalystCopperHCID 23978—
CatalystCupric ChlorideHCID 24014—
Product(2-Hydroxyethyl)iminodiacetic acidHCID 7152—

Reaction Steps

Copper titration value is used to measure the extent of biodegradation of the chelating agents during the procedure. Titration is performed using ammonium purpurate (indicator for complexometric titration, commercially available from Aldrich Chemical Co., Inc. under the trade designation Murexide) as the indicator at approximately pH 8, and using sodium acetate as buffer. Titration of 2.0 mg HEIDA (0.0105 moles) in 100 mL water with 0.01 molar copper chloride gives an endpoint of 1.06 mL, representing a 1:1 chelation of copper. Analysis is performed daily for a period of 28 days.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05726341
Source datasetuspto-grants-1998_03
ORD IDord-1fb9d43185c941be8156961fc5f37329
Source noteuspto-grants-1998_03