Aniline → HCID 23498320, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 13 g of 2-adamantanone, 55 g of aniline, and 15 g of aniline hydrochloride was introduced to a flask with a water remover. The mixture was heated and refluxed at 200° C. (oil bath) under nitrogen atmosphere. Forty hours later, a KOH solution was added so that the pH was approximately 10, and the mixture was extracted with chloroform and washed with water. The mixture was then dried with sodium sulfate, evaporated, and purified with silica gel column chromatography, to obtain 5 g of dianilinoadamantane as a colorless amorphous material.

Provenance & Evidence