HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 12132982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 12132981 | HCID 12132981 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 12132982 | HCID 12132982 | 17% |
Reaction Steps
Following the procedure of method 7D, methyl (2S)-2-[(1,2,3,3a,4,8b-hexahydrocyclopenta[b]indol-5-ylcarbonyl)amino]-3-hydroxypropanoate (8.9 mmol, 2.7 g) was hydrolyzed to the acid using 1 M aqueous lithium hydroxide (40 mL) in THF (40 mL) to yield a red oil (1.5 mmol, 430 mg, 17%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777407B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-5ab85ff43de143a48960b1884cd8e931 |
| Source note | uspto-grants-2004_08 |