HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 10275163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | N-methyl-2-oxoindoline-5-sulfonamide | HCID 10176909 | — |
| Reactant | 3-(3-(Dimethylamino)propyl)-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde | HCID 11230063 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 10275163 | HCID 10275163 | 70% |
Reaction Steps
3-(3-Dimethylaminopropyl)-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (71 mg, 0.3 mmol), 5-methylaminosulfonyloxindole (68 mg, 0.3 mmol) and piperidine (0.03 ml) in 1 ml of ethanol was stirred at 60° C. for over night. The mixture was cooled and the solids collected by vacuum filtration and washed with ethanol to give (93 mg, 70% yield) of 3-[1-[3-(3-dimethylaminopropyl)-4,5,6,7-tetrahydro-1H-indol-2-yl]-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777417B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-79dbf033942f422e91c5368bc8036f4b |
| Source note | uspto-grants-2004_08 |