N-methyl-2-oxoindoline-5-sulfonamide → 3-[1-{3-[3-(4-Methyl-piperazin-1-yl)-3-oxo-propyl]-4,5,6,7-tetrahydro-1H-indol-2-yl}-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide

Participants

Reaction Steps

3-[3-(4-Methylpiperazin-1-yl)-3-oxo-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (121 mg, 0.3 mmol) was condensed with 5-methylaminosulfonyl-oxindole (68 mg, 0.3 mmol) following the same procedure used in Example 1 to give the desired product (86 mg, 56% yield).

Provenance & Evidence