HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23498817, compound → 3-[1-{3-[3-(3,5-Dimethyl-piperazin-1-yl)-3-oxo-propyl]-4,5,6,7-tetrahydro-1h-indol-2-yl}-meth-(z)-ylidene]-5-ethanesulfonyl-1,3-dihydro-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23498817 | HCID 23498817 | — |
| Reactant | HCID 23498854 | HCID 23498854 | — |
| Product | 3-[1-{3-[3-(3,5-Dimethyl-piperazin-1-yl)-3-oxo-propyl]-4,5,6,7-tetrahydro-1h-indol-2-yl}-meth-(z)-ylidene]-5-ethanesulfonyl-1,3-dihydro-indol-2-one | HCID 60104770 | 46% |
Reaction Steps
3-[3-(3,5-Dimethylpiperazin-1-yl)-3-oxo-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde, prepared as described in Example 3 above, was condensed with 5-ethylsulfonyloxindole following the same procedure used in example 1 to give the desired product (72 mg, 46% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777417B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-5a185d53daf6486185a5212d499d1c20 |
| Source note | uspto-grants-2004_08 |