N-methyl-2-oxoindoline-5-sulfonamide → 3-[1-(3-{3-[4-(2-Hydroxy-acetyl)-piperazin-1-yl]-propyl}-4,5,6,7-tetrahydro-1H-indol-2-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide

Participants

Reaction Steps

3-{3-[4-(2-Hydroxy-acetyl)-piperazin-1-yl]-propyl}-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (134 mg, 0.3 mmol) was condensed with 5-methylaminosulfonyloxindole (76 Mg, 0.33 mmol) following the procedure used in Example 1 to give 58 mg of the desired product.

Provenance & Evidence