N-methyl-2-oxoindoline-5-sulfonamide → 2-Oxo-3-[1-[3-(3-piperazin-1-yl-propyl)-4,5,6,7-tetrahydro-1H-indol-2-yl]-meth-(Z)-ylidene]-2,3-dihydro-1H-indole-5-sulfonic acid methylamide

Participants

Reaction Steps

3-(3-Piperazin-1-yl-propyl)-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (61 mg, 0.22 mmol), prepared as described in Steps 1-3, Example 8 above, was condensed with 5-methylaminosulfonyloxindole (46 mg, 0.2 mmol) following the procedure used in Example 1 to precipitate 24 mg of the desired product as as a yellow solid.

Provenance & Evidence