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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836151Generated: October 30, 2026

HCID 23498825, compound → HCID 44299236, compound

https://huagongshe.com/reaction/1836151

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23498825HCID 23498825—
ReactantHCID 23498854HCID 23498854—
ProductHCID 44299236HCID 4429923630.8%

Reaction Steps

{(4-[3-(2-Formyl-4,5,6,7-tetrahydro-1H-indol-3-yl)-propyl]-piperazin-1-yl}-acetic acid (50 mg, 0.15 mmol), prepared as described in Example 18, was condensed with 5-ethylsulfonyloxindole (66 mg, 60% pure) following the same procedure used in example 1. The formed solid was purified by flash chromatography, eluting with (dichloromethane: methanol 8:1, 5:1:0.01 acetic acid) to give 25 mg of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777417B2
Source datasetuspto-grants-2004_08
ORD IDord-043fbd9c823941ad92c18adc0e1b0bfb
Source noteuspto-grants-2004_08