HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23498825, compound → HCID 44299236, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23498825 | HCID 23498825 | — |
| Reactant | HCID 23498854 | HCID 23498854 | — |
| Product | HCID 44299236 | HCID 44299236 | 30.8% |
Reaction Steps
{(4-[3-(2-Formyl-4,5,6,7-tetrahydro-1H-indol-3-yl)-propyl]-piperazin-1-yl}-acetic acid (50 mg, 0.15 mmol), prepared as described in Example 18, was condensed with 5-ethylsulfonyloxindole (66 mg, 60% pure) following the same procedure used in example 1. The formed solid was purified by flash chromatography, eluting with (dichloromethane: methanol 8:1, 5:1:0.01 acetic acid) to give 25 mg of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777417B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-043fbd9c823941ad92c18adc0e1b0bfb |
| Source note | uspto-grants-2004_08 |