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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836155Generated: October 31, 2026

N-methyl-2-oxoindoline-5-sulfonamide → HCID 44299354, compound

https://huagongshe.com/reaction/1836155

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
ReactantHCID 23498818HCID 23498818—
ReactantHCID 23498820HCID 23498820—
ProductHCID 44299354HCID 4429935462.5%

Reaction Steps

3-{3-[4-(2-Hydroxyethyl)-piperazin-1-yl]-propyl}-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (64 mg, 0.2 mmol), prepared by following the procedure described for 3-[3-(4-hydroxy-piperidin-1-yl)-propyl]-4,5,6,7-tetrahydro-1H-indole-2-carbaldehyde (Example 20), was condensed with 5-methylaminosulfonyloxindole (46 mg, 0.2 mmol) to give 66 mg of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777417B2
Source datasetuspto-grants-2004_08
ORD IDord-0617cc26f091401caf9585997509f7f6
Source noteuspto-grants-2004_08