HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 12017824, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 12017823 | HCID 12017823 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 12017824 | HCID 12017824 | — |
Reaction Steps
1 equivalent of DMF and 1 equivalent of oxalyl chloride are dissolved in acetonitrile at 0°. 1 equivalent of 3-[7-(3-chloro-4-methoxybenzylamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl]propionamide is then added. The mixture is stirred for one hour. After customary working up, 3-[7-(3-chloro-4-methoxybenzylamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]-pyrimidin-5-yl]propionitrile is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777419B1 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-9f13ee6438264d958dfa028331e0175b |
| Source note | uspto-grants-2004_08 |