HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 135482132, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 9836515 | HCID 9836515 | — |
| Reactant | Sodium hydroxide--water (1/1/1) | HCID 23719242 | — |
| Product | HCID 135482132 | HCID 135482132 | — |
Reaction Steps
A solution of the compound from Step C (80 mg, 0.25 mmol) in NaOH/H2O (1.6 g/20 ml) was heated at reflux for 7 hrs., whereupon the solution was adjusted with dilute HCl to a pH of 7 and then evaporated. Chromatography of the resulting solid on silica gel with EtOAc/MeOH 8/2 afforded the product as a white solid; yield 64 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777395B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-507684223f594eca813e2aaa662a7590 |
| Source note | uspto-grants-2004_08 |