反应详情

The compound of Example 22 (50 mg) and 30 mg of methyl thioisocyanate were dissolved in 1 ml of pyridine. After 2 hours of stirring at room temperature, the solvent was distilled off under reduced pressure. The residue was purified by silica gel column chromatography (elution solvent; hexane:ethyl acetate=1:2) to obtain 42 mg of the title compound. Its physical properties are shown below.

1. distillationthe solvent was distilled off under reduced pressure
2. customThe residue was purified by silica gel column chromatography (elution solvent; hexane:ethyl acetate=1:2)