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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 183635Generated: October 26, 2026

Chloride → 4-Chloro-6-(2-chloro-5-methyl-6-fluorobenzyl)pyrimidine

https://huagongshe.com/reaction/183635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
Reactant1,1-DibromoethaneHCID 11201—
ReactantZincHCID 23994—
ReactantTrimethylsilaneHCID 70435—
Reactant4,6-DichloropyrimidineHCID 70943—
Reactant6-Chloro-2-fluoro-3-methylbenzyl bromideHCID 2773680—
Product4-Chloro-6-(2-chloro-5-methyl-6-fluorobenzyl)pyrimidineHCID 22599672—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-31eb957cfb7a4f31b13db52860430682
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)