2-Methylbenzoyl chloride → HCID 69354243, compound

HRID 1836366Notes

Reaction equation

HRID 1836366 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[C:5]([CH:7]1[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)=[O:6].[CH3:17][C:18]1[CH:26]=[CH:25][CH:24]=[CH:23][C:19]=1[C:20](Cl)=[O:21]>>[CH3:17][C:18]1[CH:26]=[CH:25][CH:24]=[CH:23][C:19]=1[C:20]([NH:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[C:5]([CH:7]1[CH2:8][CH2:9][N:10]([CH3:13])[CH2:11][CH2:12]1)=[O:6])=[O:21]

Participants

3

Reactant 2

HCID 702762-Methylbenzoyl chlorideHCID 101306514-[3-Aminobenzoyl]-1-methylpiperidine

Product 1

HCID 69354243HCID 69354243, compoundYield 95%

Procedure

Beginning with 4-[3-aminobenzoyl]-1-methylpiperidine (50 mg, 0.229 mmol) and 2-methylbenzoyl chloride (90 μl, 0.687 mmol), 73.1 mg (95%) of the title compound were recovered.

Sources & evidence

ORD record
ord-667f56e246ed423fbfdff7f92dcbeea8
Source dataset
uspto-grants-2004_08
Patent number
US06777428B1

Reaction notes

Loading…