Benzoyl chloride, 3-bromo- → HCID 69356264, compound

HRID 1836367Notes

Reaction equation

HRID 1836367 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[C:5]([CH:7]1[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)=[O:6].[Br:17][C:18]1[CH:19]=[C:20]([CH:24]=[CH:25][CH:26]=1)[C:21](Cl)=[O:22]>>[Br:17][C:18]1[CH:19]=[C:20]([CH:24]=[CH:25][CH:26]=1)[C:21]([NH:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[C:5]([CH:7]1[CH2:8][CH2:9][N:10]([CH3:13])[CH2:11][CH2:12]1)=[O:6])=[O:22]

Participants

3

Reactant 2

HCID 74377Benzoyl chloride, 3-bromo-HCID 101306514-[3-Aminobenzoyl]-1-methylpiperidine

Product 1

HCID 69356264HCID 69356264, compoundYield 32%

Procedure

Beginning with 4-[3-aminobenzoyl]-1-methylpiperidine (50 mg, 0.229 mmol) and 3-bromobenzoyl chloride (91 μl, 0.687 mmol), 29.3 mg (32%) of the title compound were recovered.

Sources & evidence

ORD record
ord-60f8ea96993c405d921dbca997f9c2d6
Source dataset
uspto-grants-2004_08
Patent number
US06777428B1

Reaction notes

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