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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836383Generated: November 3, 2026

4-Chlorobenzoyl chloride → 4-[3-(4-Chlorobenzamidyl)benzoyl]-1-methylpiperidine

https://huagongshe.com/reaction/1836383

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzoyl chlorideHCID 8501—
Reactant4-[3-Aminobenzoyl]-1-methylpiperidineHCID 10130651—
Product4-[3-(4-Chlorobenzamidyl)benzoyl]-1-methylpiperidineHCID 69356110109.2%

Reaction Steps

Beginning with 4-[3-aminobenzoyl]-1-methylpiperidine (25 mg, 0.115 mmol) and 4-chlorobenzoyl chloride (29 μL, 0.229 mmol), 44.8 mg (>100%) of the title compound were recovered.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777428B1
Source datasetuspto-grants-2004_08
ORD IDord-f816e22aaf1b45da9580873f3e4c7793
Source noteuspto-grants-2004_08